南充市儿童变应性鼻炎伴发哮喘的影响因素分析
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刘海,Email:liuhai100@sina.com

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R765.21

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四川省教育厅高校创新团队项目(17TD0016);川北医学院校级课题(CBY17AYB56)。


Analysis on the influencing factors of childhood allergic rhinitis with asthma in Nanchong city
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    摘要:

    目的回顾性分析南充市3~14岁儿童确诊变应性鼻炎(AR)的变应原谱特点与伴发支气管哮喘(BA)的影响因素。方法纳入2016年9月—2019年6月川北医学院附属医院变应原检测中心,经变应原皮肤点刺实验与血清特异性IgE检测等方法确诊3~14岁AR儿童1473例, 详细采集AR儿童临床特征、变应原种类和发病诱因等资料,使用SPSS 22.0软件分析相关影响因素。结果1 473例AR儿童中,合并BA儿童309例(患病率为20.98%)。Logistic回归分析显示, AR伴发BA的危险因素分别为城市居住环境、持续性AR、AR持续时间大于3年、AR家族史、BA家族史、家中饲养宠物、被动吸烟史、早产、自行使用抗生素、粉尘螨、多主枝孢菌、艾蒿、虾以及合并鼻窦炎、变应性结膜炎、打鼾和湿疹,保护因素为母乳喂养大于3个月和年龄增大。结论南充市3~14岁AR儿童伴发BA的患病率较高。初步了解南充市AR儿童合并BA的相关影响因素,应针对其危险因素采取有效的预防措施。

    Abstract:

    ObjectiveA retrospective survey was performed on the influencing factors of childhood allergic rhinitis with Asthma, aged 3~14 years in Nanchong city.MethodsThe medical records of 1473 children with AR (3~14 years old) who had undergone allergen skin puncture test and specific IgE test in Allergen testing center, Affiliated Hospital of North Sichuan Medical College from September 2016 to June 2019 for children characteristics, allergen types and influence factors of BA by SPSS22.0.ResultsAmong the 1473 children with AR, 309 were complicated with BA(20.98%). A multiple logistic regression analysis showed that the risk factors of AR in children with BA for the urban living environment, sustainability AR, AR more than 3 years, a family history of AR/BA, Keeping pets at home, exposure to passive smoking, preterm birth, selfmedication with antibiotics, dust mites, cladosporium herbarum, mugwort, shrimp, sinusitis, allergic conjunctivitis, snoring and eczema respectively. The protective factors for BA in children with AR were breastfeeding for more than 3 months and older age.ConclusionsThe prevalence rate of BA in children with AR aged 3~14 years in Nanchong city is relatively high. Our research suggest that the influencing factors for concomitant BA in children with AR may be helpful in establishing preventive strategies of children.

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吴俊志,张震,喻望博,赵锐,朱鑫,冯成敏,敬一丹,程瑶,邓世山,刘海.南充市儿童变应性鼻炎伴发哮喘的影响因素分析[J].中国耳鼻咽喉颅底外科杂志,2020,26(6):670-675

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  • 在线发布日期: 2020-12-28
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