The patient, a 44-year-old male, was admitted to the hospital in January due to recurrent hoarseness for 1 year. Electronic laryngoscopy revealed a smooth submucosal mass on the left glottis. The patient underwent complete resection of the tumor through external cervical approach. Histopathological examination of the lesions after surgery showed a large number of lymphocytes and eosinophils infiltration. Immunohistochemical results: Vascular endothelial CD31, CD34, FLi1 and FⅧ(+),IgG (+),IgG4 (+), plasma cells showed CD38 and CD138(+),Ki-67(+), consistent with the changes of Kimura disease. At the follow-up 3 months after operation, the voice recovered well and there was no sign of recurrence in the operation area. When the diagnosis of laryngeal tumor is difficult, the possibility of this disease should be considered in combination with the increase of eosinophilia and IgE level in peripheral blood. Surgical pathology is helpful for the final diagnosis and further treatment of the disease.