Objective:To investigate the therapeutic effectiveness of sound stimulation combined with cognitive behavior therapy (CBT) on chronic tinnitus.Methods:The present research was astudy on 49 patients with chronic tinnitus who were randomly divided into intervention and control groups, and all of whom underwent sound stimulation for one month. The patients in intervention group also received personalized CBT that lasted for one month, while the patients from control group did not receive such treatment. Additionally, all patients were required to fill out the questionnaires (including THI, PSQI, SAS) before treatment and 30 days posttreatment. Results: In total, 49 cases completed the trial. The following results were observed after one month of treatment: the mean values of THI, SAS and PSQI after treatment decreased by 15.58, 15.46 and 4.96 in the control group, and 40.52, 41.76 and 7.72 in the intervention group, respectively. Thirty days posttreatment the results showed significant differences in THI (p<0.05), PSQI (p<0.05) and SAS (p<0.05). The three types of scores after intervention w4ere significantly smaller in the intervention group compared to the control group. Conclusion: Sound stimulation and CBT can predict the effectiveness of the therapy, given that the therapeutic effect of sound stimulation combined with CBT provide better results compared to sound stimulation alone. Gender, age and the hearing impairment resulted as the most relevant risk factors for tinnitus.