Objective: To explore the long-term clinical efficacy, safety, and impact on the growth and development of children with congenital choanal atresia treated with mucosal flap fabrication combined with fully degradable sinus drug stent under nasal endoscopy. Method: A retrospective analysis was conducted on 28 children diagnosed with congenital choanal atresia from January 2018 to February 2021 at Beijing Children"s Hospital affiliated with Capital Medical University. All patients were treated with nasal endoscopic mucosal flap technology combined with a fully degradable sinus drug stent system, with the indicator line of the stent system set at the external nose to self detach. Follow up at 1 month, 3 months, 6 months, 1, 2, and 3 years after surgery. Record the time when the indicator line falls off, the time when the stent is fully absorbed, the improvement of nasal congestion, and the electronic nasopharyngoscope to understand whether there are any developmental abnormalities in the nasal cavity structure, the formation of the posterior nostril, the rate of restenosis, and the incidence of complications after surgery. Evaluate the growth and development of the child according to the National Health Commission"s "Growth Standards for Children Under 7 Years" WS/T423-2022.Result: After one week of discharge, all patients had telephone consultations and their nasal congestion symptoms had disappeared. The detachment time of the indicator line of the stent system was 30.55 ± 4.75 days, and all patients completed at least two year of follow-up and a maximum of five years of follow-up. Short term follow-up (within 1 year), no reports of complications related to stent placement were found in all patients. Long term follow-up (postoperative follow-up for more than 1 year) showed that the postoperative endoscopic follow-up examination results of all patients showed that the shaping effect of the posterior nostril was stable and no restenosis was observed. Except for 3 cases where the height and weight of the children with syndrome were lower than those of their peers, the height and weight curves of the other children after 2 years of surgery were within the normal range of peers, and no effect of local nasal hormone application on the growth and development of the children was found. Conclusion:? The production of mucosal flaps and the expansion of bony posterior nostrils are key factors in ensuring the long-term efficacy of pediatric posterior nostril occlusion surgery.The application of fully degradable sinus drug stents after surgery is the key to avoiding short-term local complications. Setting up stent system indicator lines is a safe auxiliary method. Clinical observations have not found that the low-dose hormones continuously released by the stent system in the nasal cavity have long-term effects on the growth and development of children.