特发性突聋与其他疾病关联性:基于人群研究的综述
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作者单位:复旦大学附属眼耳鼻喉科医院 国家卫生健康委员会听觉医学重点实验室

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Associations between idiopathic sudden deafness and other disorders: a review of population-based studies
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EENT hospital of Fudan University

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    摘要:

    特发性突聋(即特发性突发性感音神经性耳聋,以下简称“突聋”),病因不明,可能原因为病毒感染、血管、免疫、代谢、遗传因素等。对突聋病因的探究持续不断,但目前尚无确切结论。既往国内研究多基于相对微观的个体临床检验报告。随着病例资料电子化与集成化,大数据分析技术也极大助力了疾病相关的科研工作;得益于此,国外研究也越来越多得聚焦于宏观层面、大样本量人群中,突聋与其他疾病之间的关联性研究,但结果尚有出入,也未见相关综述,不利于国人直接览读。因此,本文主要从大数据角度,对基于大规模人群研究的突聋与其他疾病的关联性报道进行文献综述,有助于从多层面、多维度对突聋病因进行归纳和调研。

    Abstract:

    The etiology of idiopathic sudden deafness (i.e. idiopathic sudden sensorineural deafness or "sudden deafness" for short) is unknown. The possible causes includes viral infection, vascular, immune, metabolic and genetic factors. The etiology of sudden deafness has been investigated continuously, but no definite conclusion has been reached. Previous domestic studies were mostly based on the relatively micro level of individual clinical examination reports. With the electronic and integrated case data, big data analysis has also greatly assisted disease-related scientific research. Benefitting from this, more and more foreign studies have focused on the correlation between sudden deafness and other diseases at the macro level and in a large sample size population. Whereas the results are still different, and no relevant review has been seen, which is not conducive to direct reading of Chinese people. Therefore, from the perspective of big data, this paper will conduct a literature review on the correlation between sudden deafness and other diseases mainly based on large-scale population studies, that is, investigate and summarize the causes of sudden deafness from multiple levels and dimensions.

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  • 收稿日期:2024-03-03
  • 最后修改日期:2024-04-26
  • 录用日期:2024-05-07
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