头颈部神经鞘瘤外科手术治疗中神经功能保护的回顾性研究
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R739.91

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2025年度湖南省科学技术厅科普专项(2025ZK4099);2024年度湖南省科学技术厅科普专项(2024ZK4141);2024年度 湖南省自然科学基金项目(2024JJ9251);2020年度湖南省肿瘤医院科研攀登计划国自培育项目(2020NSFC-B007);湖南省卫生 健康委高层次卫生人才“225”工程;2019年中央补助医疗服务与保障能力提升(医疗卫生机构能力建设)项目。


A retrospective study on the protection of neurological function in the surgical treatment of head and neck schwannomas
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    摘要:

    目的 拟通过回顾性分析手术治疗头颈部神经鞘瘤患者的临床资料,旨在为临床实践提供科学依据,优化治疗策略并提升疗效。方法 选取 2019 年 12 月—2025 年 7月于湖南省肿瘤医院收治的头颈部神经鞘瘤患者作为研究对象,纳入标准如下:①术前影像学检查提示头颈部占位;②临床资料完整;③术后病理确诊为神经鞘瘤。排除接受内镜治疗患者。本研究对神经鞘瘤患者的手术技巧、临床疗效及随访结果进行总结与分析。结果 共纳入87 例神经鞘瘤患者,病灶均位于头颈部。所有患者手术均顺利完成,完整切除率达 100%。手术时间 27~460 min,术中出血量20~500 mL。术后随访 8~66 个月,3例患者出现复发,其中1例多次复发;随访期间1例患者新发肺癌,12 例(13.8%)患者出现神经损伤症状,随访期间神经功能逐渐改善,无患者死亡。结论 头颈部神经鞘瘤手术中必要时采用显微技术可有效保留神经功能,减少并发症,结合术中神经电生理监测技术可进一步提高手术安全性。

    Abstract:

    Objective This study aims to retrospectively analyze the clinical data of patients who underwent surgical treatment for head and neck schwannomas, with the goal of providing scientific evidence for clinical practice, optimizing treatment strategies, and improving therapeutic outcomes. Methods Head and neck schwannomas treated at Hunan Cancer Hospital between December 2019 and July 2025 were selected as the study subjects. The included cases met the following criteria: preoperative imaging indicating a space-occupying lesion in the head and neck region, complete clinical data, and postoperative pathological confirmation of schwannoma. Patients who underwent endoscopic treatment were excluded. The surgical techniques, clinical efficacy, and follow-up results of these patients were summarized and analyzed. Results A total of 87 patients with schwannomas were included, and all lesions were located in the head and neck. All surgeries were successfully completed, with a total resection rate of 100%. The operation time ranged from 27 to 460 minutes, and intraoperative blood loss varied between 20 and 500 mL. During the follow-up period of 8 to 66 months, recurrence was observed in 3 patients, with one relapsed multiple times. Additionally, one patient developed secondary lung cancer, and 12 patients (13.8%) presented with neurological deficits. The neurological function gradually improved during the follow-up period, and no patient died. Conclusions The use of microsurgical techniques during schwannoma surgery, when necessary, can effectively preserve nerve function and reduce complications. The combination of intraoperative neurophysiological monitoring can enhance the safety of the surgery.

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李武,李慧,杨扬,艾昭东,李佶刚,伍鹏,周诗韦,唐宇龙,宋小花,彭小伟.头颈部神经鞘瘤外科手术治疗中神经功能保护的回顾性研究[J].中国耳鼻咽喉颅底外科杂志,2026,32(1):11-15

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  • 收稿日期:2025-07-02
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  • 在线发布日期: 2026-03-05
  • 出版日期: 2026-02-28
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